肾病综合征并发血栓栓塞的临床研究

CLINICAL INVESTIGATION ON NEPHRITIC SYNDROME COMPLICATED WITH THROMBOSIS AND EMBOLISM

目的 通过分析肾病综合征 (肾综 )并发血栓栓塞的临床特点 ,探讨预防及治疗肾综并发血栓栓塞。方法 回顾性分析肾综患者并发血栓栓塞的病例 ,分析这些患者的临床特点。结果 肾综并发静脉血栓占 60 % ,动脉栓塞占 40 %。下肢动脉栓塞 3例中 2例行截肢术。静脉血栓及肺动脉栓塞溶栓治疗有 50 %的好转率。在并发血栓栓塞的患者中 ,有一半患者有使用激素史 ,危险因素是严重低蛋白血症、高胆固醇血症。结论 肾综并发血栓栓塞以静脉血栓形成为主 ,但下肢动脉栓塞预后不良。当血白蛋白 <1 9.2 g/L ,尤其伴高脂血症时 。

Objective\ to explore a way of preventing and treating complication of thrombosis and embolism in patients with nephrotic syndrome. Methods\ The clinical data of patient with nephrotic syndrome was analyzed retrospectively . Results\ There were 60% venous thrombosis, and 40% artery embolism, and two of there artery embolism of lower limbs were amputation. Half patients had took prednisone before complication. The risk factors were hypoalbuminemia and hypercholesterolemia. Conclusions\ Venous thrombosis is main complication in nephritic syndrome.