Ⅱ期高血压病患者淋巴细胞增殖反应和白介素-2的诱生

Lymphocyte proliferation and IL-2 induction in the patients with Ⅰ stage hypertension

本文对40例Ⅱ期高血压病患者的淋巴细胞增殖反应和白介素-2(IL-2)的诱生进行了研究,结果发现淋巴细胞增殖反应和IL-2的产生明显高于正常对照组(P<0.05)。提示此两项指标的异常可能与高血压的发病机理与病理生理有关,IL-2有可能激活促进平滑肌细胞的c-fos,c-myc,c-myb基因的表达。

In this papers, lymphocyte proliferation and interleukin-2(IL-2) induction were investigated in 40 patients with I stage hypertension. The results showed that lymphocyte proliferation and IL-2 production in patients with hypertension were significantly higher than in normal control. The results suggest that the two indexes have probable relation with hypertension, and IL-2, may be able to activate or enhance expression of protoon-cogene(c-fos, c-myc, c-myb) of smooth musclar cell.