手性双噁唑啉配体的合成及其金属配合物在不对称合成中的研究近况

Synthesis of Chiral Bis-oxazoline Ligands and Recent Research of Their Metal Complexes in Asymmetric Reaction

介绍了手性双口恶唑啉配体的各种结构类型、合成方法及其金属配合物在不对称反应中的研究近况。参考文献 2

All kinds of chiral bis oxazoline ligands and their synthetic methods were discussed. They can be synthesized by the reaction between dicarboxylic acid derivatives or dinitriles with β amino alcohol, the preparation of amino alcohol is a critical step. For the biaryl ligand, Ullman reaction is a good choice. In recent years, the chiral bis oxazoline metal complexes were applied to the asymmetric Wacker-Type cyclization, Claisen rearrangement, 1,3 dipolar cycloaddition, hetero Diels-Alder reaction and diene cyclization/hydrosilylation, etc. 29 References were cited.