赛乐特联合匹维溴铵治疗肠易激综合征

Combination of Seroxat and Pinaverium bromide in the treatment of irritable bowel syndrome

目的 观察匹维溴铵、赛乐特对肠易激综合征的疗效。方法 98例随机分为两组,实验组(S组)58例,赛乐特20mg,1次/日,匹维溴铵薄膜包衣片50mg,每天3次;对照组(P组)40例;单用匹维溴铵50mg,每天3次,两组均每3天进行心理疏导1次,4周为1个疗程。结果 S组显效率58.62％,有效率37.93％,总有效率96.55％;P组显效率47.50％,有效率32.50％,总有效率80％(P<0.05)。结论 赛乐特,匹维溴铵联合治疗肠易激综合征较单用匹维溴铵疗效好。

Objective To study the effect of the Pinaverium bromide and Paroxetine on the irritable bowel syndrome (IBS). Methods The 98 cases of IBS were divided into two groups randomly. Test group ( S group) 58 cases, Paroxetine 20mg, qd, Pinaverium bromide 50mg, tid. Control group (P group)40 cases, Pinaverium bromide 50mg, tid. Both the two groups received psyche dredge once per three days. The course was four weeks. Results The effective rate of S group was 58.60% . The effective rate of S group was 37.99% .The total effective rate was 96.55% .The effective rate of P group was 47.50% . The effective rate of P group was 32 .50% . The total effective rate was 80% ( P > 0.05) . Conclusion Pinaverium bromide with paroxetine on the IBS is more effective than Pinaverium bromide alone.