前列腺肿瘤患者血清TSGF和PSA联合检测的临床意义

Clinical significance of co -detection of serum TSGF and PSA in patients with prostatic tumor .

目的探讨恶性肿瘤特异性生长因子(TSGF)和前列腺特异性抗原(PSA)的联合检测对诊断前列腺肿瘤的临床意义。方法对11例前列腺癌,14例良性前列腺增生,13例急性细菌性前列腺炎,18例慢性前列腺炎,20例正常健康体检者进行了血清TSGF和PSA水平测定。结论癌症TSGF水平明显高于良性增生、慢性炎症、健康者,与急性炎症无显著差异;癌症与良性增生的PSA水平无显著差异。TSGF、PSA对肿瘤的敏感性分别为82%、72%,联合检测的敏感性为91%。结论TSGF和PSA的联合检测对早期前列腺肿瘤的筛选有一定的价值。该方法简单、实用。

Objectives To explore the clinical value of co-detection of serum tu-mor specific grow th factor(TSGF)and prostate specific antigen(PSA)in patients with prostatic tumor.Methods Serum TSGF and PSA in11cases of prostatic cancer,14of beign prostatic hyperplasias(BPH),13of acute bacterial prostatitis(ABP),18of chronic prostatitis(CP)and20of health y persons were detected respectively.Results TSGF level of cancer cases was higher obviously than that of BPH?CP and healthy group.but not than the results of ABP and PSA levels showed no significantly different between cancer and BPH.Sensitivities of TSGF and PSA were82%and72%respectively for protatic tumors.and the sensitivity was91%by co-detection of both.Conclusions Co-detec-tion of serum TSGF and PSA is a simple and practicable method,and has clinical value to filter early prostatic tumors.