期刊文献+

国产替米考星对小白鼠的急性毒性试验 被引量:7

下载PDF
导出
摘要 采用简化寇氏法对国产替米考星在小白鼠上进行了口服急性毒性试验,结果表明,其LD50为2071mg/kg,LD50的95%可信限为1932~2219mg/kg。对小白鼠剖检结果表明,该药对内脏器官无病理损害作用,动物口服替米考星毒性很低,临床使用较完全。
出处 《兽药与饲料添加剂》 2003年第4期3-4,共2页 Veterinary Pharmaceuticals & Feed Additives
  • 相关文献

参考文献2

二级参考文献17

  • 1[2]Salmon S A,Watts J L,Case C A,et al.Comparison of MICs of ceftiofurand other antimicrobial agents against bactrial pathogens of swine from the United states,Canada,and Denmark[J].J Clin Microbiol,1995,33(9): 2435~2444.
  • 2[3]Jordan,Horrocks.The minimum inhibitory concentration of tilmicosin and tylosin for mycoplasma gallisepticum and mycoplasma synoviac and a comparison of their efficacy in the control of mycoplasma gallisepticum infection in broiler chicks[J].Avian Diseases,1996,40:326~334.
  • 3[4]Ziv G,Tov M S,Lickman A G,et al.A tilmicosin antibacterial activity and pharmacokinetics in cows [ J ].J Vet,Pharmacol Therap,1995,18:340~345.
  • 4[5]Thompson T D,Darby J M,Moran J W,et al.Tilmicosin pharmacokinetics in healthy swine[C].The 6th EAVPT Congress,1994.52.
  • 5[6]Moore,Gm & Tonkinson L V.Lilly Reserch Labs,Greenfiled,IN,USA,1992.
  • 6[7]Scorneaux B,Shryock T R.Intracellular accumulation,subcellnar distribution,and efflux of tilmicosin in bovine mammary,blood,and lung cells[J].J Dairy Sci,1999,82(6): 1202~1212.
  • 7[8]Ose E E,Tonkinson L V.Single dose treatment of neonatal calf pneumonia with the new macrolide antibiotic tilmicosin[J].Vet Rec,1988,123 (14): 367~369.
  • 8[9]Picavet T,Muylle E,Devriese L A ,et al.Efficacy of tilmicosin in treatment of pulmonary infections in calves[J].Vet Rec,1991,129(18): 400 ~403.
  • 9[10]Morch D W,Merrill J K,Thorlakson B F,et al.Prophylactic efficacy of tilmicosin for bovine respiratory tract disease[J].J Am Vet Med Assoc,1993,202(2):273~277.
  • 10[11]Walters J,Brown D R,Tarrant M E.Efficacy of pulmotil(tilmicosin inpremix form) against naturally occuring pneumonia in growing fattening pigs[C].The 6th EAVPT Congress,1994.202.

共引文献44

同被引文献18

引证文献7

二级引证文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部