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血小板膜糖蛋白及其多态性的研究 被引量：7

The study on platelet membrane glycoproteins and their polymorphism
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摘要 血小板是动脉血栓形成的主要参与者 ,其功能是通过其表面的受体糖蛋白来实现的 ,血小板膜糖蛋白的基因多态性能够改变其抗原性 ,从而影响血小板的粘附、聚集和活化反应。本文将对目前进行深入研究的几种血小板膜糖蛋白的结构、功能及其多态性进行论述。 Platelets play a key role in arterial thrombosis through their membrane glycoproteins. Inherited polymorphism within platelet membrane glycoproteins gene can alter their antigenicity, and modulate their functional properties of adhesion, aggregation and activities. This review covers the structure, function and polymorphism of several platelet membrane glycoproteins which are deeply researched.
作者 江雁
机构地区 天津市第一中心医院检验学部
出处 《中国实验诊断学》 2003年第4期281-283,共3页 Chinese Journal of Laboratory Diagnosis
基金 国家自然科学基金资助 (3 9970 182 )
关键词 血小板膜糖蛋白 多态性 研究 抗原性 platelet membrane glycoproteins polymorphism
分类号 R341 [医药卫生—基础医学]
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参考文献16

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同被引文献65

  • 1侯明,彭军.人类血小板分子免疫学研究进展[J].中国实验血液学杂志,2004,12(5):553-557. 被引量：2
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引证文献7

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中国实验诊断学
2003年 第4期

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