PCOS不孕患者血清睾酮与催乳素变化的研究

Study on Changes of Serum Testosterone and Prolactin in Sterile Patients with Polycystic Ovary Syndrome

目的 研究血清睾酮与催乳素在多囊卵巢综合征 (PCOS)不孕中的作用。方法 48例PCOS不孕患者采用放射免疫法于月经周期的第 3～ 5天取静脉血 ,分离血清 ,测定血清睾酮与催乳素的值。结果 PCOS不孕症组血清睾酮水平为3 .1± 1.4nmol/L ,其中 3 5例升高 ,占 72 .9% ;非PCOS不孕症组血清睾酮水平 2 .1± 1.2nmol/L ,两组差异显著 (P <0 .0 1)。两组血清催乳素水平分别为 17± 12及 11± 10 μg/L ,差异有显著意义 (P <0 .0 1)。 结论 PCOS不孕患者除常规测FSH、LH外 ,睾酮及催乳素水平检测是必要的。

Objective To study the role of serum testosterone and prolactin in infertile patients with polycystic ovary syndrome(PCOS).Method The values of serum testosterone and prolactin were tested with radioimmunoassay in 48 infertile patients suffered from PCOS.The specimen was collected from venous blood of the patients at the 3rd～5th day of menstrual cycle.Results Serum testosterone level in sterile patients with PCOS was 3.1±1.4nmol/L.It increased in 35 cases of them,which occupied for 72.9%,In sterile patients without PCOS,it was 2.1±1.2nmol/L.There were significant differences between two groups( P <0.01).The serum prolactin level in two groups was 17±12 and 11±10μg/L respectively.There were significant differences between two groups( P <0.01).Conclusions Besides routine determination of follicle stimulating hormone(FSH) and luteinizing hormone(LH),it is necessary to test testosterone and prolactin level in sterile patients with PCOS.