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在体大鼠膜片钳全细胞记录技术初探 被引量：1

在体大鼠膜片钳全细胞记录技术初探
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摘要 目的 :建立在体大鼠膜片钳全细胞记录方法。方法 :固定麻醉大鼠后对其顶叶皮层锥体神经元行全细胞记录。结果 :成功记录到顶叶内锥体层神经元电压门控性钠离子通道电流及自发突触活动电流。结论 :初步建立了在体大鼠膜片钳全细胞记录方法 。
作者 刘振伟 杨胜 张永祥
机构地区 军事医学科学院毒物药物研究所
出处 《中国应用生理学杂志》 CAS CSCD 北大核心 2003年第3期277-277,285,305,共3页 Chinese Journal of Applied Physiology
基金 国家自然科学基金资助项目 ( 30 171153)
关键词 大鼠 膜片钳 全细胞记录技术 在体 whole cell recording rat in vivo
分类号 Q424 [生物学—神经生物学] R338 [医药卫生—人体生理学]
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参考文献5

  • 1刘振伟,李立君,刘传缋.海马脑片盲法膜片钳全细胞记录技术[J].生理学报,2001,53(5):405-408. 被引量：24
  • 2李祥瑞,周逸峰.活体动物全细胞记录技术及其应用[J].生物物理学报,2002,18(3):287-292. 被引量：7
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共引文献27

同被引文献11

  • 1刘砚星,李学佩,刘俊秀,石葛明,路虹,马常升.水杨酸钠对大鼠下丘神经元钾通道的抑制作用[J].中华耳鼻咽喉头颈外科杂志,2005,40(11):835-839. 被引量：4
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  • 8Xu LJ, Zhao JX, Zhang T, et al. In vitro study on influence of nano particles of CuO on CAI pyramidal neurons of rat hippocampus potassium currents[J].Environ Toxicol,2009,24 (3) :211.
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中国应用生理学杂志
2003年 第3期

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