流行性出血热患者血清铁蛋白的变化及其临床意义

CLINICAL SIGNIFICANCE AND CHANGES OF SERUM FERRITIN IN THE PATIENTS WITH EPIDEMIC HEMORRHAGIC FEVER

用放射免疫法对72例各病期流行性出血热患者的血清铁蛋白进行检测,结果表明,94.4％的流行性出血热患者血清铁蛋白含量高于正常最高值,且自发热期即明显升高,持续至多尿期后部分患者才恢复正常。血清铁蛋白含量改变与流行性出血热临床类型有关。研究结果提示,血清铁蛋白的测定可作为流行性出血热有价值的辅助诊断指标之一,同时对估计病情轻重也有一定参考意义。

Serum ferritin (SF) was tested by radioimmunoassay (RIA) in 72 Patients with epidemic hemorrhagic fever (EHF)in the various phases of the disease. The results showed that the content of SF in 94.4% of the patients was above normal. It went up markedly since the febrile phase. Part of the patients didn't return to normal until diuresis phase. It was found that the change of SF was related to the clinical types of EHF. The results indicate that the determination of SF is regarded as one of the valuable and subsidiary indexes in the diagnosis of EHF, and it has a certain reference significance in the estimation of the state of illness.