36例原发胃肠道淋巴瘤的诊断和治疗

Diagnosis and therapy of primary gastrointestinal malignant lymphoma (report of 36 cases)

目的:探讨提高原发胃肠道淋巴瘤术前诊断率及治疗效果的方法。 方法:对 36例原发胃肠道淋巴瘤患者的临床表现、体征及辅助检查进行分析 ,通过 COX回归等统计方法对其预后因素及生存率等进行分析。 结果 :该病临床表现无特异性 ;诊断主要依靠内窥镜病理活检 ;手术方式、综合治疗完成情况、临床分期为与预后有关的影响因素。结论 :提高对该病临床表现及内镜、造影检查特点的认识 ,采用正确的活检方法是提高术前诊断率的关键 ;以手术及化疗为主的综合治疗措施是提高疗效的关键。

Objective: To determine how to rise the rate of preoperative diagnosis and the therapeutic efficacy of primary gastrointestinal malignant lymphoma. Methods: The clinical situation, physical signs and assitant examinations of 36 cases of primary gastrointestinal malignant lymphoma were analysed, and the prognostic factors and survival rate were analysed by COX and other medical statistic methods. Results: The clinical appearance of primary gastrointestinal malignant lymphoma was not peculiar, but had some helpful behavior; the confirmative diagnosis was mainly depended on endoscopic biopsy, surgical methods, implemental condition of multimodal therapy and stages affected the prognosis. Conclusion: To heighten the cognitive level for this disease to comprehend the behavior of the clinical, endoscopic and X ray appearance and to use a precision biopsy method are the capital of rise the rate of preoperative diagnosis; the measure of multimodal therapy that mainly depend on surgery and chemotherapy is relevant to good prognosis.