中国西部地区儿童甲状腺肿大率、尿碘、盐碘变异程度的分析

A study on the variation of goiter rates,urinary iodine and household salt iodine intake among children in West China

目的 研究影响或导致儿童甲状腺肿大率 (甲肿率 )、尿碘、盐碘三项指标变异程度的因素。方法 用设计效率 (DEFF)作为评价变异程度的指标。结果 在西部 12省中 ,儿童甲肿率的DEFF在 3.0左右的有 9个省 ,占 75 .0 % ;尿碘水平的DEFF在 1.0～ 3.5之间的有 6个省 ,占 5 0 .0 % ;合格碘盐食用率的DEFF有 11省在 3.0以上。有 4个省加碘盐覆盖率的DEFF在 3.0左右。结论 除了充分考虑非抽样因素对甲肿率、尿碘、盐碘三项指标变异程度的影响外 ,还应对西部监测中样本的数量作进一步的推算 ,使样本量这一影响指标变异程度的主要因素更加科学、合理 ,从而为全国的碘缺乏病监测工作提供科学依据。

Objective To study the factors leading to the variation of children's total goiter rates, urine iodine and salt iodine in West China. Methods Design effect (DEFF) was used to evaluate the variation of indicators. Results DEFF of children's total goiter rate was about 3.0 in 9 provinces,and the proportion was 75.0 %. The DEFF of urine iodine was 1.0- 3.5 in 6 provinces,and the proportion was 50.0 %. The DEFF of intake rate of qualified iodized salt was over 3.0 in 11 provinces.The DEFF of covering rate of iodized salt was about 3.0 in 4 provinces. Conclusion In order to provide scientific basis for IDD surveillance in China,other than bias due to methods of no-sampling, sample size should be further calculated in West China. Thus the main influencing factors of indicator variation could be measured with scientific and reasonable basis.