腭部牵张延长的实验研究

An Study of Lengthening Palate with Distraction Osteogenesis

目的 :应用自制的腭部牵张装置延长腭裂模型犬的腭部 ,探讨治疗腭咽闭合不全的新方法。方法 :用 7只健康青春期杂种雄性犬为实验对象。手术形成腭裂模型 ,在实验侧行牵张成骨术。手术当天、术后 7、1 8、60d分别取印模 ,灌注石膏模型。制作术后 60d头颅骨标本。在模型和颅骨标本上测量各标志点间的距离。结果 :实验结束时 ,动物实验侧硬腭后缘均有不同程度的后退 ,牵张间隙内为新生骨组织。结论 :应用牵张成骨术可后退腭裂模型犬的硬腭后缘 。

Objective To explore a new concept of treating velopharyngeal incompetence. Methods Seven adolescent, mix-bred dogs were used as cleft palate model. A custom-made intraoral distractor was fixed to the hard palate. After a 7-day latency period, the distractor was expanded 0.9 mm per day until it had been lengthened 10 mm. Impressions of the jaws were taken on 0d, 7d, 18d, and 60d postoperatively to examine plaster cast changes in the dental occlusion. Homogeneity of variance was also assessed using measurements of maxillary length from dental cast on 0d postoperative. Results The dental casts on 0d postoperative demonstrated all animals were homogenous with regard to facial structure in length before distraction. And the measurements of the harvested craniofacial bones showed that the length of hard palate in distraction side increased by about 5.50±0.71 mm (the rage is from 4.50 mm to 6.50 mm) and the posterior segment of the hard palate increased at about 5.30±1.26 mm (from 3.50 mm to 6.50 mm). Conclusion The hard palate of the adolescent canine cleft palate model can be lengthened with distraction osteogenesis.