摘要
目的 :建立常通口服液 (黄芪、丹参、大黄等 )的质量标准。方法 :采用高效液相色谱法对方中君药丹参中的丹参素进行含量测定 ,对黄芪、丹参、大黄进行薄层鉴别。结果 :丹参素在 1 .31～ 1 69.68μg·mL- 1 范围内 ,对照品浓度在峰面积呈良好线性关系 ,平均加样回收率为 1 0 0 .4 % ,RSD为 1 .9%。薄层图谱斑点清晰 ,阴性对照无干扰。结论 :方法简便可靠 ,精密度高 ,分离度好 。
Objective: To establish the quality standard for Changtong Oral Liquid(Radix Astragali seu Hedysarion, Radix Salviae miltiorrhizae, Radix et Rhizoma Rhei, etc.). Methods: The danshensu was determined by HPLC. Radix Astragali seu Hedysarion, Radix Salviae Miltiorrhizae, Radix et Rhizoma Rhei was identified by TLC. Results: The average recovery of danshensu was 100.4%, RSD=1.9% . A good linearity of danshensu was obtained ( r =0.9999) within the range of 1.31～169.68μg·mL. The TLC sports developed is fairly clear, and the blank test showed no interference. Conclusion: This method was simple and accurate and was not interfered by other constituents in the prescription. It could be used for the quality control of Changtong Oral Liquid.
出处
《中成药》
CAS
CSCD
北大核心
2003年第9期719-721,共3页
Chinese Traditional Patent Medicine
基金
国家新药基金课题 (课题编号 96 90 1 0 5 2 4 5)
