毒理基因组学——在基因表达水平上的环境与健康研究

Toxicogenomics ——the research of environment and health at gene expression level

毒理基因组学是在生物高通量技术手段的应用基础上发展起来的一个新的研究领域 ,主要在基因组水平上研究机体对环境因子的应答反应 ,了解基因 环境交互作用在疾病发生中的作用。本文对毒理基因组学的研究目标。

Toxicogenomics is a new scientific field that elucidates how the entire genome is involved in biological responses of organisms exposed to environmental stressors and provides profound understanding of the roles of gene environment interactions in pathogenesis of disease using high throughput technologies. In this paper, the research progress on the toxicogenomics and its application in both improving environmental health and preventing environmently related disease were reviewed.