高甘油三酯血症对动脉弹性功能的影响

Effect of Hypertriglyceridemia on arterial elasticity

目的 研究高甘油三酯血症患者动脉弹性功能的变化。方法 采用动脉弹性功能测定仪CVProfilorDo -2 0 2 0检测 12例高甘油三酯血症患者和 15例健康志愿者大动脉弹性指数C1和小动脉弹性指数C2。结果 高甘油三酯血症患者和对照组的大动脉弹性指数C1无明显差别 (13 4± 3 6vs 14 3± 3 9ml/mmHg× 10 ) ,与对照组比较 ,高甘油三酯血症患者小动脉弹性指数C2明显降低 (6 3± 1 9vs 8 5± 2 4ml/mmHg× 10 0 ,P <0 0 5 )。结论 高甘油三酯血症损伤小动脉弹性指数C2 。

Objective To study the effect of hypertriglyceridemia on arterial elasticity.Methods Large artery and small artery elasticity indices (c1 and C2) were measured in 12 subjects with hypertriglyceridemia and 15 healthy volunteers by using CVProfilorDO-2020 instrument.Results There was no difference in large artery elasticity index c1 between the two groups (13 4±3 6 vs 14 3±3 9ml/mmHg×10).However,the small artery elasticity index C2 was lower in subjects with hyperiglyceridemia than that in healthy volunteers (6 3±1 9 vs 8 5±2 4ml/mmHg×100,P<0 05).Conclusions Small artery elasticity index C2 is impaired in hypertriglyceridemic patients,indicanting that endothelial dysfunction could be responsible for the increased morbidity and mortality of coronary heart disease in hypertriglyceridemic patients.