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北京降压0号降压效应谷峰比率及平稳指数的临床研究 被引量：6

Clincal study on the trough peak ratio and smoothess index of antihypertensive effect of Beijing verticilum NO.0
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摘要 目的 探讨北京降压0号治疗轻、中度原发性高血压患者降压效应谷峰比率(T/PR)及该药的平稳指数(SI)。方法 轻、中度原发性高血压患者64例,每天旱晨8:00服北京降压0号1-2片,治疗前24 h及8周后作动态血压监测,分别以2 h个体法和整组法计算T/PR并计算该药的ST。结果 8周治疗后患者偶测血压和动态血压的降低幅度分别为(21.8±11.0),(17.9±8.0)mmHg和(16.4士2.5)/(13.8±2.2)mmHg,个体法计算的收缩压和舒张压的T/PR分别为0.778±0.210、0.747±0.240,而整组法则分别为0.782和0.749,该组的收缩压和舒张压SI分别为3.97和3.82。结论 北京降压O号可24 h有效平稳的降压,其降压平稳的作用可通过T/PR.和SI反映。
作者 郑海容 董丽 张长青
机构地区 山东省兖矿集团鲍店矿医院内科
出处 《疑难病杂志》 CAS 2003年第4期223-224,共2页 Chinese Journal of Difficult and Complicated Cases
关键词 原发性高血压 北京降压0号 降压效应 谷峰比率 平稳指数 治疗
分类号 R544.1 [医药卫生—心血管疾病] R972.4 [医药卫生—药品]
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参考文献6

  • 1叶任高.内科学.第5版[M].北京:人民卫生出版社,2002.809～810.
  • 2Proposed guidelines for the clinical evaluation of antihypertensive drug products(draft).Rockville Md:Federal Drug Administration Division of Cardio-Renal Drug Products,1988.4.
  • 3Lipicky RJ.Trough peak ratio:the rationale behind the united states Food and Drug Administration recommendations.J Hypertens,1994,12(S8):17.
  • 4Omboni S,Fogari R,Palatini P,et al.Reproducibility and clinical value of the trough-to-peak ratio of the antihypertensive effect:evidence from the sample study.Hypertension,1998,32:424-429.
  • 5李玉杰,麦炜颐,曾群英,廖晓星,王礼春,陈国伟.控释硝苯地平降压效应谷 /峰比率的临床研究[J].中国临床药理学与治疗学,2001,6(2):138-141. 被引量：3
  • 6Parati G,Omboni S,Rizzoni D,et al.The smoothness index:a new,reproducible and clinically relevant measure of the homogeneity of the blood pressure reduction with treatment for hypertension.J Hypertens,1998,16(11):1 685-1 691.

二级参考文献12

  • 1Kloner RA, Vetrovec GW, Materson BJ, et al. Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients. Am J Cardial.1998;81:163
  • 2Alderman MH, Cohen H, Roque R, et al. Effect of long-acting and short-acting calcium antagonists on cardiovascular outcomes in hypertensive patients. Lancet.1997;349:594
  • 3Wurdeman RL, Mooss AN, Mohiuddin SM,et al. Comparison of 24 hour ambulatory blood pressure date in hypertensive patients switched from nifedipine-GITS to nifedipine-CC. Pharmacotherapy.1999;19:94
  • 4Parati G, Omboni S, Rizzoni D, et al. The smoothness index: a new, reproducible and clinically relevant measure of the homogeneity of the blood pressure reduction with treatment for hypertension.J Hypertens.1998;16(11):1685
  • 5Proposed guidelines for the clinical evaluation of antihypertensive drug products (DRAFT) Rockville. Md: Federal Drug Administration Division of Cardio-Renal Drug Products,1988:4
  • 6Elliott HL, Meredith PA. Trough peak ratio, clinically useful or practically irrelevant? J Hypertens,1995;13:279
  • 7Myers MG. Trough-to-peak ratio and 24hour blood pressure control: methodological issues. Am J Hypertens,1995;8:214
  • 8Omboni S, Fogari R, Palatini P, et al. Reproducibility and clinical value of the trough-to-peak ratio of the antihypertensive effect. Evidence from the sample study. Hypertension,1998;32:424
  • 9Mallion JM, Maitre A, de-Galldemaris R, et al. Use of ambulatory blood pressure monitoring in the management of antihypertensive therapy.Drugs,1992;44(suppl)1:12
  • 10Lipicky RJ. Trough peak ratio: the rationale behind the united states Food and Drug Administration recommendations. J Hypertens,1994;12(S8):S17

共引文献32

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引证文献6

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疑难病杂志
2003年 第4期

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