期刊文献+

TF相关性抗原与肿瘤的关系

Thomsen-Friedenreich-related antigen and tumors
下载PDF
导出
摘要 TF(Thom sen- Friedenreich,TF)相关性抗原是一组与肿瘤相关的糖抗原决定簇 ,在多种肿瘤中均有表达 ,且与肿瘤的生物学行为及其预后因素密切相关 ,对肿瘤的诊断、治疗和预后有重要意义。本文对 TF抗原与消化系统肿瘤、肺癌、乳腺癌等多种恶性肿瘤之间的关系进行了综述 ,并初步讨论了该抗原在肿瘤诊治。 The Thomsen Friedenreich(TF) related antigen is a group of tumor related carbohydrate epitopes expressed in several kinds of tumors, and it is closely related with the biological behavior and prognosis of tumor. TF antigen also has great significance in the diagnosis and therapy of tumors. This article reviewed the relation between TF antigen and several kinds of malignant tumors such as the tumor in digestive system, pulmonary carcinoma and mastocarcinoma.The diagnostic, therapeutic and prognostic value of the TF antigen is also primarily discussed.
作者 朱雄伟 王强
出处 《第二军医大学学报》 CAS CSCD 北大核心 2003年第8期899-901,共3页 Academic Journal of Second Military Medical University
关键词 TF相关性抗原 肿瘤 糖抗原决定簇 生物学行为 预后 诊断 治疗 预后 Thomsen Friedenreich related antigen neoplasms
  • 相关文献

参考文献16

  • 1Hanisch FG, Baldus SE. The Thomsen-Friedenreich (TF) antigen: A critical review on the structural, biosynthetic and histochemical aspects of a pancarcinoma-associated antigen[J]. Histol Histopathol, 1997,12(1) : 263-281.
  • 2Cao Y,Karsten UR,Liebrich W,et al. Expression of Thomsen-Friedenrich-related antigen in primary and metastatic colorectal carcinoma[J]. Cancer ,1995 , 76(10) :1700-1708.
  • 3Baldus SE,Zirbes TK,Hanisch FG,et al. Thomsen-Friedenreich antigen presents as a prognostic factor in colorectal carcinoma: A clinicopathologic study of 264 patients [J].Cancer,2000,88(7) : 1536-1543.
  • 4Baldus SE, Hanisch FG, Kotlarek GM,et al. Coexpression of MUC1 mucin peptide core and the Thomsen-Friedenriech antigen in colorectal neoplasams [J]. Cancer, 1998, 82(6) : 1019-1027.
  • 5Singh R, Campbell BJ, Yu LG, et al. Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominately carried on high molecular weight splice variants of CD44[J].Glycobiology, 2001,11(7) : 587-592.
  • 6Baldus SE,Zirbes TK,Glossmann J,et al. Immunoreactivity of monoclonal antibody BW835 represents a marker of progression and prognosis in early gastric cancer[J]. Oncology, 2001,61(2) : 147-155.
  • 7Kurtenkov O, Miljukhina L, Smorodin J, et al. Natural IgM and IgG antibodies to Thomsen-Friedenreich (T) antigen in serum of patients with gastric cancer and blood donors-relation to Lewis (a,b) histo-blood group phenotype[J]. Acta Oncol,1999,38(3) :939-943.
  • 8Yoshida A,Sotozono M,Nakaton T,et al. Different expression of Tn and sialy-Tn antigens between normal and diseased human gastric epithelial cells[J]. Acta Med Okayama, 1998, 52(4):197-204.
  • 9Flucke U ,Zirbes TK,Schroder W,et al. Expression of mucin-associated carbohydrate core antigens in esophageal squamous cell carcinomas[J]. Anticancer Res,2001,21(3C) :2189-2193.
  • 10Cao Y,Karsten U,Otto G,et al. Expression of MUC1,Thomsen-Friedenreich antigen, Tn, sialosyl-Tn and alpha2,6-linked sialic acid in hepatocellular carcinoma and preneoplastic hepatocellular lesions[J]. Virchows Arch, 1999,434(6) : 503-509.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部