摘要
目的 糖化血红蛋白 (HbA1c)测定是监测血糖控制程度的重要指标 ,在糖尿病 (DM)的治疗和血管并发症的防治中起着重要作用。方法 采用微柱法 (离子交换层析 ,BIO RAD试剂 ) ,测定了 87例糖尿病患者的全血HbA1c含量 ,并对该方法进行了一般性评价。结果 当DM控制较好时其浓度值在 <6 .2 %范围内 ;当DM控制较差时其浓度可高至正常的 2~ 3倍。即HbA1c浓度 >8% ,说明血糖控制程度差 ,提示临床增加用药量 ;HbA1c浓度在 7%~ 1 0 %范围提示血糖控制程度较好 ,如HbA1c浓度 <6 %说明治疗效果好 ,血糖已降至正常或无糖尿病水平。结论 血液中的葡萄糖测定仅反映即刻血糖水平 ,而HbA1c值可判断
Objective To investigate the clinical significance of glycated hemoglobin A 1c (HbA 1c ) and its role as a useful clinical marker in the evaluation for the glucose metabolism in patients with diabetes mellitus . Methods The 87 patients with diabetes mellitus were enrolled into the study. HbA 1c were testes with micro column test in the diabetes mellitus . Results Prevalence rates of HbA 1c <6.2% , HbA 1c 6.2~8.0% and HbA 1c >8.0% were 32.18%, 31.04%,36.78% respectively in 87 diabetic patients. Conclusion Blood glucose is only a marker for instant plasma glucose level . Measurement of HbA 1c is significant in evaluation of the two months average level of glycemic excursion and HbA1c is closely correlate to clinical manifestation of patients with diabetes mellitus.
出处
《辽宁医学杂志》
2003年第4期185-186,共2页
Medical Journal of Liaoning