维生素K_3的表面增强拉曼光谱研究

A Study of Vitamin K_3 by Surface Enhanced Raman Scattering

首次报道了维生素K3 (VK3 )分子的常规拉曼光谱 (NRS)及该分子在活性衬底银镜上的表面增强拉曼散射 (SERS) ,并对它的拉曼特征谱带进行了初步的指认和归属。通过对比VK3 的常规拉曼光谱和SERS谱 ,发现VK3 分子吸附在银表面后拉曼散射强度被大大增强了。另外 ,VK3 的羰基与银粒子发生电荷转移后形成负离子自由基 ,碳氧双键打开。受VK3 分子吸附在银镜表面的影响 ,萘环结构发生了很大的扰动 ,导致一些拉曼特征峰产生位移 ,环变形振动对应的拉曼散射强度得到了增强。这些研究结果为SERS技术今后对VK3进行药物检测以及痕量分析方面的应用提供了依据。

The normal Raman spectrum(NRS)of vitamin K-3 molecules and surface enhanced Raman scattering (SERS) of these molecules adsorbed on active silver mirror substrate are reported in this paper. Assignments of the Raman bands for VK3 molecules are presented. By comparison, the results show that the intensity of Raman scattering was, enhanced on account of vitamin K-3 molecules adsorbed on silver mirror substrate. In addition, the free group of negative ion came into being as a result of charge transfer between C=O band of vitamin K-3 molecules and silver particles, and the C=O band was opened. The interaction between vitamin K-3 molecules and silver surface made a large disturbance to the structure of naphthalene ring, and resulted in some Raman shifts and the enhancement of ring deformation vibration. These results provide information about the application of SERS techniques to trace detection and quantitative analysis of druggery.