摘要
目的 :观察三种治疗方法对围绝经期抑郁症患者的疗效。方法 :对围绝经期患者出现焦虑与抑郁情况进行评估 ,行SDS评分。将确诊为抑郁症的 12 0例随机分为 3组 :激素连续性序贯治疗组 (A组 )、心理治疗加氟西汀治疗组(B组 )、心理治疗加氟西汀及激素连续序贯治疗组 (C组 )各 4 0例 ,疗程均为 3个月。治疗 3个月后行HDRS评分 ,了解治愈情况。结果 :C组疗效明显优于A、B组 ,均差异有显著性 (P <0 .0 1,0 .0 5 ) ;A组和B组的疗效比较则差异无显著性 (P>0 .0 5 )。结论 :采用C组治疗方法对围经期抑郁症患者疗效良好且疗效肯定 ,值得推广。
Objective:To observe the efficacy of three therapeutic regimens for perimenopausal women with depression.Methods:A total of 120 perimenopausal women with depressive disorder were randomly divided into 3 groups:group A,B and C received estrogen/progestogen treatment,psychotherapy/fluoxetin and psychotherapy/fluoxetin plus estrogen/progestogen treatment,respectively.Clinical improvement of depressive symptoms was assessed with the Hamilton depression rating scale (HDRS) at baseline and at endpoint of treatment (3 months).Results:The therapeutic efficacy in group C was superior to that in group A and B ( P< 0.05 0.01),but there was no significant difference between group A and B ( P> 0.05).Conclusion:Psychotherapy/fluoxetin plus estrogen/progestogen treatment is an efficacious treatment for perimenopausal women with depression.
出处
《广东医学院学报》
2003年第4期344-345,共2页
Journal of Guangdong Medical College
关键词
围绝经期
抑郁症
激素替代治疗
氟西汀
心理治疗
perimenopause
depression
hormone replacement therapy
fluoxetin
psychotherapy
