间室切除在四肢软组织肿瘤治疗中的应用

Application of compartment resection in patients with extremity soft tissue sarcomas

目的:探讨间室切除术在四肢软组织肿瘤治疗中方法及临床价值。方法:12例四肢软组织肿瘤,上肢2例,下肢10例,首次治疗者8例,复发者4例。行股前间室切除术3例,股后间室切除术7例,前臂外侧间室切除1例,三角肌全切除1例。伴神经部分切除术2例。功能重建包括肌腱替代和皮瓣转位等。结果:本组均保留患肢,随访10～60个月,无瘤生存10例,复发和死亡各1例。结论:对于四肢软组织肿瘤,以控制肿瘤和保存肢体为治疗核心,间室切除术系目前较理想的方法。

Purpose: The purpose of this study was to assess the method of compartment resection and evaluate its application to patients with extremity soft tissue sarcomas. Methods: From 1997 to 2002, 10 cases of thigh sarcoma underwent this operation (7 cases of posterior compartment and 3 anterior compartment) while 2 cases with upper limb disease received similar resection. Results: All the limbs of this group with such tumors were preserved. We followed up the 12 patients in the range of 10 to 60 months, 10(82%) were alive without tumor recurrence or metastases. One patient local with recurrent tumor is receiving radiotherapy now and another died from distance metastases. Conclusions: This improvement in the rate of limb -preserving resection in our series has been the result of compartment resection.