食品和公共场所从业人员HBV感染情况调查分析

The Survey of Infection Status of Food and Public Places Personnel from 1995 to 2002 in Tianhe District in Guangzhou City

目的 了解本辖区食品和公共场所从业人员乙型病毒性肝炎(HBV)感染情况及其分布特点及HBsAg阳性与HBeAg和ALT(谷丙转氨酶)之间的相互关系。方法 采用酶联免疫吸附试验(ELISA),对1995—2002年本辖区食品和公共场所从业人员进行HBsAg、HBgAg检测和ALT测量。结果 1995—2002年共检测568 193人份,其中HBsAg阳性人数为55151人份,HBeAg阳性人数为18940人份,ALT异常人数为878人份。1995—2002年HBsAg检出率分别为9.81％、10.97％、11.58％、11.98％、9.36％、8.46%、9.21％和7.69%。1995—2002年HBeAg检出率分别为3.51%、3.95%、3.93%、3.63％、2.93%、3.06%、3.48％和2.48％。ALT1995—2002年异常人数检出率分别为0.25％、0.23％、0.27％、0.30％、0.10％、0.07％、0.06％、0.06％。结论 本辖区食品和公共场所从业人员HBsAg感染率有所下降,但下降趋势不明显,HBeAg检出率和ALT异常人数检出率较低且每年相对稳定。建议 健全食品和公共场所从业人员健康体检制度,进一步加强卫生监督。

OBJECTIVES To know the infectious status and distribution speciality of hepatitis B virus in food and public places personnel in this district, and the correlation of positive HBsAg and HBeAg with ALT. METHODS Enzyme-linked immunoabsorbent assay was used to test the HBsAg and the HBeAg and ALT of food and public places personnel from 1995 to 2002 in this area. RESULTS The 568 193 serum sample was examined, which it account for 55 151 positive serum sample of HBsAg and 18 940 of HBeAg and 878 of ALT. The rate of infection and carriers of HBsAg were 9. 81% , 10.97% , 11.58% , 11.98% ,9.36% , 8. 46% ,9. 21% and 7. 69% respectively, and of HBeAg were 3. 51% ,3. 95% ,3. 93% ,3. 63% ,2. 93% ,3. 06% ,3.48%and2. 48% .respectively, of ALT was 0. 25% ,0. 23% ,0. 27% , 0. 30% , 0. 10% , 0. 07% , 0. 06% > and 0. 06% , respectively. CONCLUSIONS The infectious rate of food and public places personnel declined lightly, and the declining tendency was insignificant. The rate of infection and carriers of HBsAg and HBeAg were lower, and which it was relatively steady. We suggested to take the comprehensive measures to control food and public places personnel physical examination, and then to strengthen health sup(?)ision.