河北省某县有偿献血丙型肝炎病毒感染者血清抗HIV检测分析

Findings of anti-HIV tests in persons infected by HCV after blood transfusion in one county of Hebei Province

目的 调查并分析河北省某县有偿献血员中丙型肝炎病毒 (HCV)感染者艾滋病病毒I型 (HIV 1)感染情况。方法 采用实时定量聚合酶链反应 (PCR)和酶联免疫吸附试验 (ELISA)法等检测了抗 HCV、HCV核糖核酸 (RNA)和抗 HIV。结果 共检测 10 9例受HCV感染的献血员 ,其中ALT异常者为 3 8 53 % ( 4 2 /10 9) ,抗 HCV阳性率为 95 41% ( 10 4/10 9) ,HCVRNA阳性率为 70 64% ( 77/10 9) ,抗 HIV阳性率为 0 ( 0 /10 9)。结论 在该县有偿献血HCV感染者中HIV 1感染率为 0 ,HCV感染者中HIV 1感染存在地区差异 。

objective To analyze the condition of HIV-1 infection in the person i nf ected by HCV after blood transfusion in one county of Hebei Province. Method Anti -HCV, HCV RNA and anti-HIV were detected using real time PCR and ELISA. Results In 109 Persons infected by HCV, 38.53%(42/109) was ALT abnormal, 95.41%(104/109) was anti-HCV positive and 70. 6 4%(77/109) was HCV RNA positive, whereas all were anti-HIV negative. Conclusions No HIV-1 infection was found in the blood donors infected by HCV in this count y in Hebei Province. There is difference in the susceptibility to HIV-1 infectio n s from counties to counties. Not all counties have the same high infection rate of HIV-1 in HCV carriers in Hebei Province.