对HIV流行地区人群抗庚型肝炎病毒抗体的调查

A survey of hepatitis G virus in a HIV endemic region.

目的 在艾滋病病毒 (HIV)流行地区调查庚型肝炎 (庚肝 )病毒 (HGV)的感染率 ,并探讨其对HIV /AIDS患者病情进展的影响。方法 对某HIV流行地区 647名村民询问病史 ,检测血清抗 HGV和抗 HIV。结果 647人中检测出抗 HGV 3 3 3例 ( 51 5% ) ,抗 HIV 3 2 8例 ( 50 7% ) ,混合感染HGV和HIV 2 10例 ( 3 2 5% ) ;其中≥ 2 0岁、有供血浆史或HIV感染者是HGV感染的高危人群。HIV感染合并HGV人群与不合并感染HGV人群相比较 ,其患AIDS或AIDS死亡者所占比例较低。结论 供血浆传播是造成该地区HGV和HIV流行的主要原因 。

objective To estimate the prevalence of HGV/GBV-C in a HIV endemic re g ion and discuss the effect of HGV on HIV clinical progress. Methods ELISA was ap plied to detect HGV-Ab and HIV-Ab in villagers who were interviewed in the HIV e ndemic region. Results Out of 647 villagers, 333 (51.5%) were HGV-Ab positive, 328 (50.7%)-HIV-Ab positive and 210 (32.5%) were found to be co-infected. Th e prevalence rate of HGV infection was high in the villagers who were over 20 year s, being plasma donors and HIV-infected. However, the proportion of the co-inf ec ted patients who were ADIS or died of AIDS was comparative low. Concl usion Paid plasma donors were the main source of HGV and HIV epidemic. Co-infection with H GV can probably slow the progress of HIV/AIDS.