102例慢性胃炎患者舌象定量分析

Quantitative Analysis of Tongue Conditions in 102 Cases of Chronic Gastritis

为研究慢性胃炎患者舌苔脱落细胞化学成分检测与不同证型之间的关系 ,利用细胞化学和图像分析系统检测10 2例慢性胃炎患者舌苔脱落细胞中葡萄糖 6 磷酸脱氢 (G 6 PDH)、琥珀酸脱氢酶 (SDH)、糖原 (PAS)的含量变化。结果 :PAS平均灰度值比较 ,脾气虚弱组较正常组显著降低 (P <0 0 1) ,其他各证型均较正常组明显升高 (P <0 0 1) ,其中肝胃郁热兼肝郁气滞组最高 (P <0 0 1) ;SDH平均灰度值比较 ,除肝胃郁热兼肝郁气滞组外 ,其他各证型均较正常组明显升高 (P <0 0 1～ 0 0 5 ) ,其中 ,湿浊中阻组较脾气虚弱组升高 (P <0 0 5 )。各证型G 6 PDH平均灰度值均较正常组升高 ,湿浊中阻组、湿浊中阻兼脾气虚弱组、脾气虚弱组明显升高 (P <0 0 1)。提示舌苔脱落细胞化学成分检测可以作为慢性胃炎中医辨证的客观参考指标之一。

To determine the contents of G-6-PDH, SDH and PAS in the exfoliated cells of tongue coating of the patients with chronic gastritis of different syndromes, their contents in 102 cases were detected. Results: In term of the mean grey value of PAS, the value in the patients with spleen-qi deficiency syndrome is less than that in the normal people (P<0.01); but the value in other syndromes rose obviously (P<0.01), especially in the syndrome of stomach-heat and liver-qi stagnation (P<0.01). As to the mean grey value of SDH, except for the syndrome of liver-stomach heat and liver-qi stagnation, the value of SDH in other syndromes obviously rose (P<0.01-0.05), with higher value in dampness-turbidity syndrome than in spleen-qi deficiency syndrome (P<0.05); the mean grey value of G-6-P in any other groups was higher than that in normal group (P<0.01). It is revealed that the chemical ingredients of exfoliated cell of tongue coating can be used as one objective index for the syndrome differentiation of chronic gastritis.