长QT综合征的临床特点和治疗

Clinical characteristcs of patients with long QT syndrome and individualized therapy

目的 :总结 9例先天性长QT综合征 (LQTS)的临床特点及相应的治疗效果。方法 :采集 9例患者的临床病史 ,接受静息和运动心电图、超声心动图及电解质检查 ,随访观察治疗效果。结果 :9例中 ,8例发作与运动或情绪激动有关 ,使用普奈洛尔或普奈洛尔加起搏器治疗 ;1例在睡眠中发病 ,使用临时起搏器加美西律治疗。1例因停药死亡 ,其余随访效果满意。结论 :针对LQTS患者的临床特点采用相应的治疗 。

Objective:To find the characteristics of patients with long QT syndrome and the effects of individualized therapy.Methods:Basic and exercise elctrocardiogram (ECG) were recorded and used to analyze the pattern of the T wave and change of QT interval. Patients accepted individualized therapy according to the clinical characreristics and ECG patterns. Syncope and QT interval prolongation were provoked or wrosen by emotonal stress or exercises in 8 patients, of whom, ECG pattern of LQT1, in 3 patients, LQT2 in 5 patients. The orther 1 patient had syncope attacks during sleep and ECG pattern of LQT3.Results:The data of follow up showed 8 patients had satisfactory results after accepting corresponding therapy.Conclusion:Individualized therapy according to the clinical characteristic and ECG patterns should be provided to the patients with long QT syndrome.