荷叶水提物对人体高脂血症的降脂效果研究

Effects on water extract of lotus leaf to Improve in Human's Blood Lipids Disorder

目的 为了探讨荷叶水提物对人体高脂血症的降脂效果。方法 从郴州市各类人员体检检出的高脂血症者中 ,选择符合高血脂诊断标准的自愿者 ,共 6 2人。随机分成 2组 ,每组 31人 ,即荷叶组与对照组。荷叶组服用荷叶水提物制作的胶囊 ,3次 日 ,4粒 次 ;对照组给予安慰剂 ;两组同时进行健康教育和膳食指导 ,治疗 4 0天。采用日本产全自动生化分析仪 (OLYMPUS - 6 4 0 )测定治疗前后血清TC、TG、HDL -C和LDL -C水平。结果 荷叶组治疗后血清TC、TG、LDL -C水平明显下降 ,HDL -C明显升高 ,与治疗前有显著差异 (P <0 .0 0 1,0 .0 0 1,0 .0 0 2 ,0 .0 1) ;对照组治疗前后血清TC、TG、LDL -C和HDL -C水平无显著差异 (P >0 .0 5 ) ,且治疗后的血脂水平明显高于治疗组 (P <0 .0 1)。结论 荷叶水提物对人体具较好的调脂作用 ,而且未发现毒副作用。

Objective To explore the role on water extract of lotus leaf to improve Human's blood lipid disorder . Methods 62 hyperlipemia volunteer were chosen from health examination in inhabitants of Chenzhou, randomly divided into 2 groups with 31 cases in each group-lotus leaf group and control groups. The test period was 40 days. Lotus leaf capsule was taken 3 times every day with 4 pills each time in lotus leaf group ; placebo was taken in control group . Health education was given in two groups. The blood lipids (TC、TG、HDL-C、LDL-C) were measured by OLYMPUS-640 before and after treatment. Results In lotus leaf group , the serum level of TC、TG、LDL-C after treatment was significantly lower than that of before treatment (P<0.001, 0.001,0.002, 0.01), and HDL-C was significantly higher (P<0.01); In control group ,there were not significant differences in the serum level of TC、TG、LDL-C、HDL-C before and after treatment (P>0.05). Conclusions The water extract of lotus leaf can improve blood lipid disorder without any toxicity.