摘要
[目的]探讨肝癌合并肝功能不全介入治疗的相应对策。[方法]1993年7月～2001年10月间350例肝癌合并肝功能不全的患者,依据异常指标的不同分为四组:A组谷丙转氨酶(sGPT)大于120U/L,129例;B组阻塞性黄疸,总胆红素(TBIL)50μmol/L^300μmol/L,51例;C组为凝血酶原时间(PT)延长超过17秒,50例;D组有A、B、C组两种以上情况的120例。对sGPT升高、PT延长的患者都经药物治疗sGPT<100U,PT<17秒后行超选择的肝动脉化疗栓塞术(TACE);梗阻性黄疸的患者直接行肝动脉灌注化疗术(TAI);然后比较介入前后肝功能及肿瘤情况并随访4组的生存情况。[结果]4组介入治疗后都有一过性肝功能轻度损害,B组黄疸指数多数有下降,4组的肿瘤基本上有缩小;4组的平均生存期分别为(10±3.0)个月、(9±2.3)个月、(9.3±2.6)个月、(8±1.5)个月。[结论]针对肝癌合并肝功能不全急性指标异常的不同采用相应的治疗是必须的,也是有效的。
To investigate the method of interventional therapy for t reatmant of hepatic carcinoma com-plicaled with liver dysfunction.From July1997to October2001,350cases with hepatic carcinoma,ac-cording to the diffe rent liver dysfunction,were divided into four groups:Group A(129cases),sGPT>120U/L;Group B(51cases),with obstructive jaundice and total bilirubin(TBIL)50～300μ mol/L;Group C(50cases),PT>17's and Group D(120cases),GPT>120U/and PT>17's. After taking medicine,the GPT and PT dropped to100U/L and17's respectively.In G roup A,C and D the patients were treated by transarterial chemoembolization(TACE )after the sGPT drop to100U/L and PT down to17's;but in Group B the patients we re treated by transarterial infusion.The liver functions and mass size and survi val were compared among four groups.Almost all mass were shrunk.The s urvival time in:Group A was10ent liver functions.
出处
《肿瘤学杂志》
CAS
2003年第5期296-298,共3页
Journal of Chinese Oncology
关键词
肝肿瘤
肝功能
介入疗法
hep atic neoplasms
liver function
interventional therapy
