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EGFR单抗与肿瘤治疗进展 被引量：3

EGFR Monocolonal Antibody and Progression in Tumor Therapy
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摘要 表皮生长因子受体 (EGFR)是原癌基因c erb B1的表达产物。通过与其配体结合而表现出生物学效应 ,其过表达和突变体借助于信号转导使细胞生长失控和恶性化 ,从而导致肿瘤的发生。基于此优点成为目前肿瘤治疗的新靶点。制备出针对对其的特异性抗体将给肿瘤治疗带来新的希望。
作者 范建华 赵建阳 成国祥
机构地区 上海转基因研究中心 上海转基因研究中心
出处 《中国肿瘤生物治疗杂志》 CAS CSCD 2003年第3期221-222,共2页 Chinese Journal of Cancer Biotherapy
基金 上海市科技发展基金 (0 2 43 1910 5 )
关键词 表皮生长因子受体(EGFR) 单克隆抗体 肿瘤治疗
分类号 R730.5 [医药卫生—肿瘤]
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参考文献15

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二级参考文献2

共引文献7

同被引文献24

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中国肿瘤生物治疗杂志
2003年 第3期

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