脑安滴丸抗大鼠血栓形成及抑制血小板聚集作用

Effects of Nao′an Dropping Pill on Antithrombosis and Inhibiting Platelet Aggregation

目的 :观察脑安滴丸 ( NDP)抗血栓形成及抗血小板聚集作用。方法 :利用实验性体内血栓形成测定仪、体外血栓形成测定仪、血小板聚集仪等测定血栓形成时间、血栓干重及湿重、血小板最大聚集率。结果 :NDP高、低剂量组均能延缓体内血栓的形成 ,减少体外血栓的形成量 ,并可明显抑制血小板聚集。上述 3项指标与生理盐水对照组相比差异有显著性。结论

Objective: To observe the effect of Nao′an dropping pill on anti thrombosis and inhibiting platelet aggregation. Methods: The time of thrombosis, dry weight and wet weight of thrombus and maximum aggregation rate of platelet were measured by instruments. Results: Nao′an dropping pill can delay thrombosis in vivo, decrease the weight of thrombus in vitro and obviously inhibit platelet aggregation. Conclusion: Nao′an dropping pill can inhibit thrombosis and platelet aggregation.