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支气管哮喘患儿血清sICAM-1的研究

Analysis of serum sICAM-1in children with bronchial asthma
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摘要 目的:探讨可溶性细胞间粘附分子-1(sICAM-1)在小儿支气管哮喘中的作用。方法:应用酶联免疫吸附法(ELISA法)测定55例哮喘患儿和30例健康儿童血清sICAM-1水平。结果:血清sICAM-1水平检测哮喘组高于对照组,发作期高于缓解期。结论:血清sICAM-1参与了支气管哮喘的发病过程。 Objective To study the effects of sICAM-1on children with bronchial asthma.Method The level of sICAM-1in serum was measured by enzyme linked immunoabsorbent assay(ELISA)in55children with asthma and30healthy children.Results The serum level of asthma group is higher than that of control group and the attack period level is higher than remission period level.Conclu sion The serum sICAM-1take part in the attack of asthma.
出处 《吉林医学》 CAS 2003年第4期317-318,共2页 Jilin Medical Journal
关键词 小儿 支气管哮喘 可溶性细胞间粘附分子-1 酶联免疫吸附法 sICAM-1 Bronchial asthma Enzyme linked immunoadsorbent assay(ELISA)
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参考文献4

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  • 2Hirata N, Kohrogi H, lwagoe H, et al. Allergen exposure induces the expression of endothelial adhesion molecules in passively sensitized human bronchus:time course and the role of cytokines[J]. Am J Respir Cell Mol Biol, 1998;18(1):12.
  • 3Striz I, Mio T, Adachi Y, et al. IL-4 induces ICAM-1 expression in human bronchial epithelial cells and potentiates TNF-alpha[J]. Am J Physiol, 1999;277(1 Pt 1):58.
  • 4Oymar K, Bjerknes R.Differenfial patterns of circulating adhesion molecules in children with bronchial asthma and acute bronchiohtis[J].Pediatr Allergy Immunol, 1998;9(2):73.

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