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冠心病患者载脂蛋白B100基因突变的研究 被引量:1

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摘要 目的:探讨冠心病发病基因水平上的原因,为冠心病的诊断提供理论依据[1]。方法:采用PCR与限制性内切酶MspI酶切方法对182例冠心病患者进行了载脂蛋白B100基因突变的研究。结果:73例心绞痛病例中,基因水平有改变者为18例(42%);9例心肌梗死患者基因水平有改变者3例(33.3%),余者基因水平无改变。结论:冠心病患者中心绞痛和心肌梗死两类冠心病部分病人病因与其基因水平碱基突变有关。
出处 《吉林医学》 CAS 2003年第4期335-336,共2页 Jilin Medical Journal
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