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角膜缘干细胞移植术治疗翼状胬肉的疗效观察(附100例报告) 被引量:2

Limbus corneoscleral stem cell transplantation in treating pterygium:with a report of 100 cases
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摘要 目的 :评估角膜缘干细胞移植术治疗翼状胬肉的疗效。方法 :对 10 0眼行翼状胬肉切除联合角膜缘干细胞移植术 ,术后随访半年以上 ,与既往行翼状胬肉切除联合带蒂球结膜转移术的 10 0眼对照。结果 :实验组治愈 85例 ,好转 10例 ,复发 5例。对照组治愈 70例 ,好转 2 2例 ,复发 8例 ,2组差异有显著性 (P <0 .0 5 )。结论 :角膜缘干细胞移植可提高手术疗效。 Objective:To evaluate the effect of limbus corneoscleral stem cells transplantation on pterygium. Method:100 eyes were performed pterygium resection and limbus corneoscleral stem cells transplantation ,observed over 6 months ,and were contrasted with other 100 eyes that were performed by pterygium resection and pediculate bulbar conjunctiva transplantation.Results :In treatment group , 85 eyes were cured ,10 eyes improved , 5 eyes were recrudesced . In the 100 contrasted eyes ,the corresponding figures were 70 ,22 and 8 respectively.The effect of the treatment group was much better than that of the control one. The differences was significant (P<0.05) . Conclusion: The effect can be improved evidently by applying limbus corneoscleral stem cells transplantation.
作者 刘澍 陈国民
出处 《山东大学基础医学院学报》 2003年第4期232-233,共2页 Journal of Preclinical Medicine College of Shandong Medical University
关键词 角膜缘干细胞移植术 手术治疗 翼状胬肉 疗效 临床观察 Pterygium Surgery ,eye Treatment outcome
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  • 1徐国兴,周琳英,童绎,梁平,林发森,陈莲云.翼状胬肉超微结构的病理研究[J].中华眼科杂志,1996,32(6):438-440. 被引量:52
  • 2Vaughan DG, Asbury T, Riordan - Eva P. General Ophthalmology[ M ]. 14th ed. New York : Appleton, 1995.117.
  • 3Schemer A , Galvin S, Sun TT. Differentiation- related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells[J] .J Cell Biol , 1986,103(4) :49.
  • 4Tsubota K .Treatment of serve ocular - surface discords with corneal epithelial stem - cell transplation[J]. N Engl J Med , 1999,3(3) :1698 - 1703.
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  • 1徐国兴,Invest Ophthalmol Vis Sci,1995年,36卷,1027页

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