男性不育症中医证型与精液参数及血清性激素关系的初步探讨

Relationship between the TCM-Type of Male Infertility and Laboratory Results of Semen and Serum Sex Hormone

目的 :探讨男性不育症各中医证型与精液及性激素检测结果的关系。 方法 :98例男性不育症病人分成肾阳虚组、肾阴虚阻、痰湿内蕴组、肝郁血瘀组、兼夹证组 5组 ,进行精液常规及性激素检测 ,性激素采用化学发光酶免疫法。 结果 :精液常规检查中 ,与肾阴虚组比较 ,肾阳虚组精子密度和活率较低 (P均 <0 .0 1 ) ;肝郁血瘀组精子活率较低 (P <0 .0 1 )、活力也较低 (P <0 .0 5) ;性激素检查中 ,与肾阳虚组比较 ,肾阴虚阻、痰湿内蕴组、肝郁血瘀组睾酮均比肾阳虚组高 (P <0 .0 5) ,其中肾阴虚组的黄体生成素 (LH)、卵泡生成素 (FSH)比肾阳虚组低 (P <0 .0 5 ,P <0 .0 1 )。 结论 :男性不育症中医证型与精液常规中精子密度、活率以及血清性激素之间有一定的关系。

Objective: To explore the relationship between the TCM type of male infertility and the laboratory results of sex hormone. Methods: Ninety eight patients with male infertility were divided into 5 groups: Shenyangxu, Shenyinxu, Tanshineiyu, Ganyuxieyu and Jianjiazheng. Semen and blood samples were taken from each patient. Then both semen routine and serum hormone tests were performed, in which CLIA was used with sex hormone. Results: The routine test of semen showed that Shengyangxu group had a lower semen count ( P < 0.01 ) and a lower survival ratio ( P < 0.01 ) than shenyinxu group. Ganyuxieyu group had a lower survival ratio ( P < 0.01 ) and inferior motility ( P < 0.01 ). While the sex hormone test, showed that the Shenyinxu, Tanshineiyu, and Ganyuxueyu group had a higher level of testosteone ( P < 0.05 ) than Shenyangxu group, and Shenyinxu group had a lower level of LH, FSH than Shenyanxu group ( P < 0.05 , P < 0.01 ). Conclusions: Some relationship does exist between the TCM type of male infertility and semen count, survival ratio and serum T, LH, FSH concentration.