肠球菌的耐药现状调查

Investigation into the current status of the drug resistance of enterococci

目的 对肠球菌的耐药现状进行分析研究,监测医院感染肠球菌耐药菌株的流行状况。方法 对湖北地区9所综合医院感染标本中分离的318株肠球菌进行鉴定和药敏试验,以“WHONET4”软件分析。结果 氨苄青霉素耐药的肠球菌(ARE)分离率为16.98％;氨基糖甙类高水平耐药的肠球菌(HLAR)分离率为37.76％;万古霉素耐药肠球菌(VBE)的分离率为0,HLAR合并ARE的分离率为5.66％。结论 肠球菌耐药呈上升趋势,其医院感染在湖北地区呈散在流行趋势。临床微生物室应严密关注VRE的检出及其流行播散。

Objective To analyze the current status of the drug resistance of enterococci and monitor the prevalence of drug-resistant strains of enterococci in hospital infection. Methods 318 strains of enterococci separated from infectious samples in nine general hospitals in Hubei were assayed and tested with regard to drug sensitivity and the software of WHONET4 was used to analyze the data. Results The separation ratio of ARE, HLARE, VRE and ARE complicated with HLARE was respectively 16.98% , 37.76% , 0 and 5.66% . Conclusion The drug resistance of enterococci shows the tendency of increasing and consequent hospital infection shows the tendency of scattered prevalence. Laboratories of clinical microorganisms ought to closely watch the detection and spread of VRE.