摘要
目的 了解广东汉族人α1-抗糜蛋白酶信号肽基因的分布特点 ,并与其它地区人群进行比较。方法 应用聚合酶链反应技术对正常人α1-抗糜蛋白酶信号肽基因进行扩增以BstNI进行限制性酶切图谱分析。结果 广东汉族人α1-抗糜蛋白酶信号肽基因中 ,表现型T/T频率是 5 0 0 % ,表现型T/A是 37 2 % ,表现型AA是 12 8%。α1-抗糜蛋白酶信号肽基因T频率是 0 6 2 2 ,基因A频率是 0 378。结论 广东汉族人α1-抗糜蛋白酶信号肽基因的分布与其它地区及人种有不同。
Objective: To identify the distribution feature of α1-antichy-motrypsin (AACT) gene in the Hans in Guangdong Province. Method: α1-antichy-motrypsin (AACT) genes from normal individuals were amplified with PCR and their restricted enzyme digested maps analysis were done with Results: AACT genotypeT/T frequence:50.0%,genotypeT/A frequence:37.2%;genotypeAA frequence:12.8% T allelel frequence:0.622;Aallele frequence:0.378. Conclusion: The AACT genes distrbution in the Hans in Guangdong province is different from those in other areas.
出处
《中国优生与遗传杂志》
2003年第3期17-18,共2页
Chinese Journal of Birth Health & Heredity
