Ⅱ型糖尿病并发症发生特点与影响因素的研究

CASE-CONTROL STUDY ON EPIDEMIOLOGICAL CHARACTERISTICS AND DETERMINANTS OF TYPE Ⅱ DM COMPLICATIONS

目的 :了解 型糖尿病 (DM)并发症的发生情况 ,分析和评价影响因素 ,为延缓和控制其发生 ,提供防治方案的参考依据。方法 :利用某矿区 DM现况调查资料进行 型 DM并发症发生特点及影响因素的研究。结果 :4 6 .89%的 型 DM患者患有不同程度的并发症 ,显著高于 NGT(血糖正常 )者 (16 .2 0 % ) ,其中高血压、脑血管病、高脂血症、肾病及视网膜疾病是 型 DM患者的常见并发症。在新诊断的 91例 型 DM患者中 ,72 .5 3%已出现 DM症状 ,39.5 6 %同时伴有一种及以上并发症。多因素非条件 L ogistic回归分析结果显示 10个变量与 型 DM并发症发生有正向或负向统计学关联。多因素分析在调整其他因素的影响和控制混杂因素后未发现 DM病程与 型 DM患者并发症的显著性关联 ,可能与病程的确定有关。结论 :发现影响 型 DM患者并发症发生的因素的特点。

Objective:To analyze the epidemiological characteristics,and evaluate the determinants of TypeⅡDM complications.Methods: A population based case-control study was carried out based on the prevalence survey of DM in a mining district. Results: 46.89% of TypeⅡDM patients had DM complications in various degrees,more higher than that of NGT cases(16.20%),and hypertension,cerebrovascular disease,hyperlipemia,nephropathy,retinopathy were the main TypeⅡDM complications.Among the 91 TypeⅡ DM cases diagnosed in the survey,72.53% of them had DM symptoms,while 39.56% of them accompanied with one and more complications.The non-conditional Logistic regression analysis found that there were 10 variables such as meat,junior high school education level,legume products,2h blood glucose after eating,age,SBP,taking zoo cooking oil,light-color vegetable,corn,home wife had positive or negative statistic relationships with TypeⅡDM complications(model G value was 57.9008, P< 0.0001).Age,intake of more meat and legume products,high SBP,high 2h blood glucose after eating are risk factor of TypeⅡDM complications,while occupational physical activity,corn,and taking light-color vegetable maybe the protective factors.After adjusted other factors and controlled confounding factors,the relationship between the course of DM and Type Ⅱ DM complications wasn't found,it maybe related to the decision of course.Conclusion:The study provide some valuable clews to the further discussion of TypeⅡDM complications' determinants.