常用抗结核药物对医院内感染的影响

The Influence of Appliance of Anti-tubercle Drug on Nosocomial Infection

目的 探讨抗结核药物对医院内获得性感染的影响。 方法 观察住院治疗的 189例肺结核患者在治疗期间发生医院内感染的情况并加以分析。 结果 抗结核治疗者医院内获得性感染发生率明显高于未抗结核治疗者 ,感染发生率随抗结核治疗时间的延长而升高 ,不同方案抗结核药物对院内感染的发生有不同影响 ,其中以利福平影响最大。 结论 长期使用抗结核药物治疗也是引发医院内获得性感染的原因之一 。

Objective To discuss the influence of anti-tubercle drug on nosocomial infection. Methods Observe the condition of the occurrence of nosocomial infection in 189 TB in patients during treatment period Result The rate of nosocomial infection in patients who received anti-tubercle is higher than those who didn't. The rate rises with the extension of appliance of anti-tubecle drug. Different regimen drug has different influence on nosocomial infection, among which Rifampici is the strongest one. Conclusion Long-term applianc of anti-tubercle drug is one of the causes resulting in nosocomial infection, which must be attentive.