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SLL和CLL病理形态与免疫组化的鉴别诊断 被引量:1

Differential Diagnosis of the Morphopathology and Immunohistochemistry of Small Lymphacytic Lymphoma and Chronic Lymphatic Leukemia
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摘要 报道8例SLL和CLL的临床、病理和免疫组化的特征。尤其是B-SLL/CLL有隐结节、前淋巴细胞、副免疫母细胞;T-SLL/CLL扭核细胞、HEV,具有病理诊断价值。由于免疫表型不同,区別T或B-SLL/CLL是可能的,但要区别B-SLL/CLL或者区別T-SLL/CLL是十分困难的。目前已有报道L20MCAb与B-SLL和CLL起反应,而Aol MCAb只与B-CLL起反应,故Aol MCAb能区別B-SLL和CLL。 This article reports the clinical,pathological and immunohistochemical characteristics of eight cases of SLL and CLL. Findings especially valuable to the pathological diagnosis are pseudofollicular, pro lymphocytes and paraimmuno blast of B-SLL/CLL and twisted-nucleus cells and HEV of T-SLL/CLL. Owing to the difference in immunophenotype, it is possible to distinguish T-SLL/CLL from B-SLL/CLL. But the differentiation of T-SLL from T-CLL and B-SLL from B-CLL is extremely difficult. There are reports about reactions of 120 MCAb with B-SLL and CLL. But A 01 MCAb, which only reacts with B-CLL, is considered able to discriminate B-SLL from CLL.
出处 《南京医学院学报》 CSCD 1992年第1期34-38,共5页
关键词 淋巴瘤 淋巴细胞 白血病 鉴别诊断 small lymphacytic lymphoma chronic lymphatic leukemia differential diagnosis immunohistochemical
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