5-邻羟基苯基-10,15,20-三苯基卟啉的微波合成

The Microware Synthesis of 5-(2-hydroxyphenyl)-10,15,20-triphenylporphyrin

利用微波加热 ,在丙酸介质中 ,以苯甲醛、水杨醛和吡咯按 3∶ 2∶ 4的用量 ,合成了 5 -邻羟基苯基 - 10 ,15 ,2 0 -三苯基卟啉 ,产物经红外光谱、紫外可见光谱进行了表征。该方法的最大优点是大大地缩短了反应时间 ,节约了能源 ,同时使产品分离纯化操作更为简单。在加热 8min后 ,粗产品经柱层析 ,产率可达到 4 .5 %。

A new method microwave irridation was employed in the experiment to synthesize 5 (2 hydroxyphenyl) 10,15,20 triphenylporphyrin in the presence of propanoic acid. The characterization of the product is shown through IR and UV spectra. The new method possesses the following major advantages the reactional time is reduced, energy is saved ,and the synthetic operation is simple. After 8 minute irridation, the raw product was separated column chromatography and its yield reached 4.5% .