子宫内膜间质肉瘤13例临床病理分析

Clinical analysis of 13 cases with endometrial stromal sarcoma

目的 提高子宫内膜间质肉瘤的早期诊断率 ,以确定手术范围 ,避免二次手术。方法 对 13例子宫内膜间质肉瘤临床病理资料进行回顾性分析。结果 确诊主要依靠病理结果 ,术前诊断性刮宫结合宫腔镜 ,宫颈赘生物活检确诊率为 6 0 % (3/ 5 ) ;临床分期为 期 11例 , 期 1例 , 期 1例 ;行全子宫及双侧附件 (包括次广泛 )切除 6例 ;行全子宫切除或全子宫及单侧附件切除 5例 ,残端复发灶切除 1例 ,行宫颈赘生物摘除 1例 ;术后 11例行全身化疗。结论 对此类患者 ,术前诊断性刮宫是必要的。疑有恶性应送冰冻病理检查 ;

Objective\ The purpose of this study was to improve the early diagnosis rate and determing the surgical extent to avoid the second operation.Methods\ Retrospective analysis was performed on 13 cases with endometrial stromal sarcoma.Results\ Diagnosis was mainly confirmed by pathologic results.The diagnostic rate of combined diagnostic D&C(dilatation and curettage)and biopsy neoplasm of cervix was 60%(3/5).There were stage Ⅰ 11 cases,stage Ⅱ 1 cases,stage Ⅳ 1 case.Total bysterectomy and bilateral salpingo oophorectomy were performed in 6 cases,total hysterectomy and single salpingo oophorectomy or total hysterectomy 5 cases,total biopsy neoplasm of cervix 1 case.Chemical therapy was performed in 9 cases ofter surgical treatment.Conclusion\ It is necessary for these patients to undergo diagnostic dilatation and curettage.The specimen of uterine myoma during surgical treatment must be examined at once,and should have a frozen section for examination if it is necessary.The best curative effect is chemical therapy after total hysterectomy and bilateral salpimgo oophorectomy.