摘要
随着对不孕症研究的深入,发现高泌乳素(PRL)血症是黄体功能不全的重要原因之一,临床应用妇孕Ⅰ号新方治疗高泌乳素血症性黄体功能不全之不孕症,取得了良好的疗效,总有效率达91.2％。但其机制尚不明了,本实验主要从内分泌角度观察妇孕Ⅰ号新方的作用,为临床探讨补肾调肝方药改善黄体功能提供理论依据。
No. 1 Pregnancy Prescription is composed of Fluoritum, Radix Dipsacl, Rhizoma Dioscoreae, Redix Angelicae Sinensis, Paeoniae Alba, Radix Bupleuri. Ramulus Uncariae cum Uncis. and Radix Glycyrrhizae. Using rats as the experimental animals, the author has found that (1) this drug call an- tagonize the effect of metoclopramide on pregestin and estrogen and this is in consistence with the find- ings in clinical practice; (2) it can increase the weight of the rat's uterus and ovary; and (3) it can promote the formation of corpus luteum and maturity of follicle.
