参附注射液对肺癌患者围手术期免疫功能的调节作用

The effect of shenfu injection on human immune function at lung cancer patients.

目的研究肺癌患者围手术期免疫功能情况及参附注射液的调节作用。方法 32例肺癌患者根据病理学结果随机分为治疗组和对照组 ,治疗组患者从手术前 3天到术后 14天 ,每天静脉滴注参附注射液 5 0ml,手术过程中静脉滴注 5 0ml;对照组除不用参附注射液外 ,其它条件与治疗组相同。于术前、术毕、术后 3天、术后 14天抽取静脉血监测补体C3 、C4,免疫球蛋白IgG、IgA、IgM ,C反应蛋白 (CRR)和血常规。结果术后 3天、7天 ,治疗组患者血浆补体C3 、C4和C反应蛋白、白细胞总数明显低于对照组 (P <0 .0 5 ) ;而免疫球蛋白IgG、IgA、IgM则明显高于对照组 (P <0 0 5 ) ;中性粒细胞分类 (N % )两组无显著性差异 (P >0 0 5 )。结论参附注射液对肺癌患者围手术期免疫功能有较好的调节作用。

Objective To investigate the effects of shenfu injection on human immunomodulation at lung cancer patients. Methods 32 cases lung cancer patients were divided into test group(n=16)and control group(n=16),The test group patients were administrtived with shenfu injection of 50ml for intravenous drip before 3 days and after 14 day operation and 50ml were administratived in operation.Results The changes of the plasma complement(C 3,C 4),immunoglobulin(IgG、IgA、IgM),C reaction protein (CRP)and blood routing parameters etc.were significantly different than those in control group on different times (P<0.05).Conclusion Shenfu injection is an advantageous condition on human immunomodulation at lung cancer patients.