甲状腺机能亢进性肌病的临床和肌电图研究

Clinical and electromyographic Study in patients with thyrotoxic myopathy

目的 :探讨肌电图在甲状腺机能亢进 (甲亢性肌病 )性肌病中的临床应用价值及其与甲状腺素、病程和性别的关系。方法 :对 38例甲状腺功能亢进患者进行神经传导速度测定及肌电图检查。结果 :38例甲亢患者运动神经及感觉神经传导速度正常 ,9例肌力减退者运动单位电位 (MUP)时限缩短 ,2 9例肌力正常者中 ,MUP时限缩短者 16例。男性患者MUP时限缩短的发生率高于女性 ,T3、T4增高者MUP时限缩短的发生率高于T3、T4正常者。病程短于 4个月者MUP时限缩短的发生率较高。结论 :EMG检测可发现亚临床甲亢性肌病 ,MUP时限为较敏感和客观的指标 ,并与性别。

Objective:To explore the clinical applicational value of EMG in patients with thyrotoxic myopathy,and its relation with the thyro oxyindole levels,the course of disease and the sex. Methods:NCV and EMG were done in thirty eight patients with hyperthyroidism.Results:Normal MCV and SCV were observed in all the 38 patients.Nine(including 7ones complicated with periodic paralysis) patients with reduced muscle strength showed decreased duration of motor unit potential (MUP).In 29 patients with normal muscle strength,16 of them showed decreased duration of MUP.The occurrence rate of decreased MUP duration in males was higher significantly than that in females.It was higher in patients with course of disease less than 4 months than in those with course of disease more than 4 months,in patients with increased level of T3?T4 than in those with normal T3?T4 levels.Conclusion:EMG might detect subclinical thyrotoxic myopathy.Duration of MUP might be a more sensitive and objective index,and it might be related with the sex,the leved of thyro oxyindole and the course of disease.