糖尿病与非糖尿病患者急性心肌梗死血脂分析

Lipidic change in early acute myocardial infarction patients with or without diabetes mellitus

目的 探讨糖尿病与非糖尿病患者并发急性心肌梗死时血脂水平变化及临床意义。 方法 以我院心内科收治的 2 3例糖尿病合并急性心肌梗死患者为观察组 ,与 4 4例非糖尿病急性心肌梗死对照组进行比较。观察指标为血甘油三酯、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、低密度与高密度脂蛋白胆固醇比值、甘油三酯与高密度脂蛋白胆固醇比值。 结果 观察组的甘油三酯 (TG) (P <0 0 1)、总胆固醇 (TC) (P <0 0 5 )含量及甘油三酯 高密度脂蛋白胆固醇比值 (TG HDL C) ( P <0 0 5 )明显高于对照组 ,而低 高密度脂蛋白胆固醇比值 (LDL C HDL C) (P >0 0 5 )两组无明显统计学差异。

Objective To investigate the lipidic change in early(≤24 hours) acute myocardial infarction(AMI) patients with or without diabetes(control group) Methods Plasma-cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C) and high density lipoprotein cholesterol(HDL-C) were measured in 23 AMI patients with diabetes and 44 AMI patients without diabetes,the ratio of TG to HDL-C (TG/HDL-C) and LDL-C to HDL-C(LDL-C/HDL-C) was estimated by calculation Results TG(P<0 01)、TC(P<0 05) and TG/HDL-C(P<0 05) in diabetes group were significantly higher than that control group and there was no obvious statistic difference in LDL-C/HDL-C between the two groups(P>0 05) Conclusion Serum-lipidic di- sorders in the early AMI were different between patients with and without diabetes