摘要
目的 探讨人类乳头状瘤病毒感染与鼻息肉发病的相关性。方法 取70例鼻息肉组织标本,用HPY-DNA-Typing方法进行人类乳头状瘤病毒(HPV-DNA)检测及病毒分型,24例正常鼻腔粘膜作对照。结果70例鼻息肉中有19例(27.14％)HPV-DNA感染,24例正常鼻腔粘膜中1例感染HPV-DNA(4.17％),HPV分型发现以HPV-5型为主。结论 鼻息肉发病可能与HPV感染有一定关系。
Objective To explore pathogensis of nasal polyp. Methods To detect HPV in 70 nasal polyp samples by HPV-DNA-TYPNING. Twenty-four cases of normal nasal mucous were used as control. Results HPV-DNA was positive in 19 cases (27.14%) of 70 cases. Only one case of control was positive (4.17%) in 24 normal nasal mucous. The most HPV type detected was HPV-5. Conclusion The results showed that HPV plays an etiologic role in the development of nasal polyp.
出处
《中国耳鼻咽喉颅底外科杂志》
CAS
2003年第4期220-222,T002,共4页
Chinese Journal of Otorhinolaryngology-skull Base Surgery
