地尔硫卓治疗顽固性心绞痛

Effect and Safety of Intravenous Herbesser in Controlling Obstinate Angina Pectoris

目的 观察静脉点滴地尔硫卓对顽固性心绞痛的临床疗效和安全性。 方法 对 12 6例顽固性心绞痛患者静脉滴注地尔硫卓观察心绞痛发作次数 ,持续时间以及血压、心率变化 ,地尔硫卓不同剂量疗效比较 ,副作用及临床疗效。 结果 静滴地尔硫卓 4 8h心绞痛平均发作次数减少 (0 8± 0 2次比 7 2± 2 1次P <0 0 0 1) ;发作时间缩短 (11 6± 5 5min/次比 17 2± 6 5min/次 ) ,75 %的患者在用药期间未再发作心绞痛 ,其中 5 2例因静点硝酸甘油 4 8h不能缓解而改用地尔硫卓静点 4 8h内未再出现心绞痛。 结论 静脉滴注地尔硫卓对顽固性心绞痛有较好的疗效和安全性。

Objective To investigate the effect and safety of intravenous Herbesser in controlling obstinate angina pectoris. Methods 126 patients with obstinate angina pectoris were treated with intravenious Herbesser.The clinical efficacy,blood pressure,heart rate and adverse effects were analyzed. Results Number of times of angina pectoris reduced obviously(0.8±0.2 vs 7.2±2.1,P<0.001) and continue time shortened (11.6±5.5 vs 7.2±6.5,P<0.001).75% Patients are successful in intravenious Herbesser.In 52 patients there were not clinical efficacy with intravenous Nitroglycerin but there were not angina pectoris after using intravenous Herbesser.Conclusion Intravenous Herbesser is safe and high clinical efficacy.