牙周引导组织再生术治疗根分叉区骨缺损临床观察

Guided tissue regeneration in the treatmentof furcation defects

目的 :对引导组织再生术治疗Ⅱ°～Ⅲ°根分叉区骨缺损的近期临床疗效进行评价。方法 : 选取Ⅱ°～Ⅲ°根分叉区骨缺损患牙 2 1个 ,牙周引导组织再生术 (GTR)治疗 11个 ,常规翻瓣术治疗 10个 ,术后 3个月观察附着水平、牙周袋深度的变化 ,通过计算机测量分析根尖片 ,对两种手术方法进行比较。结果 :术后 3个月 ,两组牙周袋探诊深度自身对照 ,有明显改善 ,差异有显著性 (P <0 .0 5 )。GTR组临床附着水平有明显改善 ,且有显著性差异 (P <0 .0 5 ) ,翻瓣组临床附着水平变化则无显著性差异 (P >0 .0 5 ) ;GTR组与翻瓣术组比较 ,各项临床指标均有显著性差异 (P <0 .0 5 )。计算机测量分析根尖片 ,GTR组较翻瓣组垂直向骨高度增加显著 ,有统计学意义 (P <0 .0 5 )。结论 :治疗Ⅱ°～Ⅲ°根分叉区骨缺损 ,GTR术可获得良好的近期临床疗效。

Objective:To evaluate the clinical effect of GTR in the treatment of degree Ⅱ～Ⅲ furcation defects with expanded polytetrafluoroethylene(ePTFE) membranes.Method:21 sites with Ⅱ～Ⅲ furcation defects were selected and divided into two groups. One group received GTR treated with ePTFE membranes. The other group received flap operation. Clinical measurements and standardized radiographs analyzed by computer were used to evaluate the effect.Result: At 3 month after surgery, we compared the pre- and post- treatment clinical measurements. All of the clinical parameters were significant difference (P< 0.05) except the flap operation group' attachment levels (AL) gain. As compared to the flap operation, all the clinical parameters measured in GTR group were significant difference (P< 0.05). The radiographs showed the alveolar bone in the two groups became more density. The vertical bone gain was significant difference between the GTR group and flap operation group (P< 0.05). Conclusion:In this short-term study, we found that the degree Ⅱ～Ⅲ furcation defects treated with GTR can gain good results.