期刊文献+

风湿免疫疾病患者应用英夫利西单抗不良反应的观察及护理

下载PDF
导出
摘要 目的:观察风湿免疫疾病患者注射英夫利西单抗的不良反应发生情况,并探讨相应的护理方法。方法:收集2013年1月~2014年2月于本院进行治疗的71例风湿免疫科患者的临床资料并做回顾性分析,针对出现的不良反应采取针对性的护理措施。结果:所有研究对象下输注英夫利西单抗后共有5例发生不良反应,4例表现为皮肤黏膜反应,1例表现为呼吸心血管系统反应,2例表现为胃肠道反应,1例出现感染。早期发现与处理,症状均得以缓解。结论结论:针对性的护理干预措施可显著降低输注过程中不良反应的发生,有利于患者顺利完成英夫利西单抗治疗计划,达到减缓病情进展的目的。 Objective:To observe rheumatoid immune disease patients infliximab to adverse reactions occur, and explore the corresponding nursing methods. Method:Collected from January 2013 to February 2013 in our hospital for treatment of 71 cases of patients with li rheumatism lead and make a retrospective analysis of clinical data, appeared on the adverse reaction of corresponding nursing measures.Results:All the research object of infusion infliximab after a total of 5 cases of adverse reactions, 4 cases of skin mucous membrane reaction, 1 case of respiration cardiovascular system response, 2 cases of gastrointestinal reaction, 1 case of infection.Early detection and treatment, the symptoms eased.Conclusion:Targeted nursing intervention can significantly reduce the occurrence of adverse reactions in the process of infusion, beneficial to patients with complete infliximab treatment plan, achieve the goal of slow disease progression.
机构地区 达州市中心医院
出处 《中国妇幼健康研究》 2016年第S1期158-159,共2页 Chinese Journal of Woman and Child Health Research
关键词 英夫利西单抗 不良反应 风湿免疫疾病 护理 Infliximab Adverse reactions Rheumatoid immune diseases nursing
  • 相关文献

参考文献7

二级参考文献106

  • 1施苏青.从1例“输液反应”谈护士与药物不良反应[J].现代中西医结合杂志,2006,15(17):2419-2420. 被引量:2
  • 2侯勇,张奉春,黄烽,吴东海,鲍春德,倪立青,姚晨.Infliximab治疗类风湿关节炎的随机双盲平行多中心临床试验[J].中华风湿病学杂志,2006,10(11):658-663. 被引量:34
  • 3王莉莎,黄烽,张江林,邓小虎,张亚美,张莉芸,郭军华.肿瘤坏死因子拮抗剂在治疗强直性脊柱炎中的安全性分析[J].中国新药杂志,2007,16(7):556-561. 被引量:24
  • 4CHOY EH, PANAYI GS. Cytokine pathways and joint inflammation in rheumatoid arthritis[J]. N Engl J Med, 2001, 344(12): 907-916.
  • 5RIGBY WF. Drug insight: different mechanisms of action of tumor necrosis factor antagonists-passive-aggressive benavior? [J]. Nat Clin Pract Rheumatol, 2007, 3(2): 227-233.
  • 6SCALLON B, CAI A, SOLOWSKI N, et al. Binding and functional comparisons of two types of tumor necrosis factor antagonists[J]. J Pharmacol Exp Ther, 2002, 301 (2): 418-426.
  • 7St CLAIR EW, van DER HEIJDE DM, SMOLEN JS, et al. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial[J]. Arthritis Rheum, 2004, 50( 11 ) : 3432-3443.
  • 8GOEKOOP-RUITERMAN YP, de VRIES-BOUWSTRA JK, ALLAART CF, et al. Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study) : a randomized, controlled trial [J]. Arthritis Rheum, 2005, 52(11 ) : 3381-3390.
  • 9MAINI RN, BREEDVELD FC, KALDEN JR, et al. Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate[J]. Arthritis Rheum, 2004, 50(4) : 1051-1065.
  • 10van DER BIJL AE, GOEKOOP-RUITERMAN YP, de VRIESBOUWSTRA JK, et al. Infliximab and methotrexate as induction therapy in patients with early rheumatoid arthritis[J]. Arthritis Rheum, 2007, 56(7): 2129-2134.

共引文献77

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部